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Bio Complete Serum

With Patented Heparan Sulfate Analog + Sustained Release Retinoids
30 mL | 1.0 FL OZ

A gentle vitamin A serum with patented Heparan Sulfate Analog (HSA) technology, Senté Bio Complete Serum is the ultimate anti-aging solution for sensitive skin and first-time retinol users. Our revolutionary HSA molecule repairs damage while slow-release retinoids boost cell turnover without irritation, producing smoother, younger-looking, and a more even skin tone within eight weeks.

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Doesn't clog pores



Paraben free

Gluten free

Cruelty Free

Time-Release Retinol for Sensitive Skin

Senté Bio Complete Serum with proprietary HSA technology and sustained-release retinoid is perfect for those who want to reap retinoid’s rejuvenating benefits without all of its irritating side effects. This medical-grade vitamin A serum is formulated in a slow-release delivery system to prolong the retinoid’s action over time. If you have sensitive skin, this is your chance to experience retinoid’s rejuvenating benefits. Unlike other retinols, Senté Bio Complete Serum helps decrease redness and dryness due to its hydrating formula.

  • 100% of subjects showed improvement in skin texture in eight weeks

Impressively Effective. Surprisingly Gentle.

This lightweight vitamin A serum contains gentle, skin-boosting active ingredients that help reverse signs of aging. Our proprietary HSA molecule helps promote repair from within as slow-release retinoids boost cellular function, revealing more youthful-looking skin with minimal risk of irritation.


The combination of HSA and retinoids in Senté Bio Complete Serum means you are benefiting from two powerful, efficacious components known to rejuvenate damaged skin.

The low molecular weight of Heparan Sulfate Analog in Senté’s vitamin A serum allows for improved skin absorption to help target the underlying causes of inflammation that cause damage. HSA supports the skin’s natural ability to repair itself, leading to healthier-looking skin with less visible redness, dryness, and fine lines and wrinkles.

Together with retinoids, Senté’s rejuvenating serum delivers unparalleled anti-aging benefits. Sustained-release retinoids are delivered gradually to increase cell turnover and stimulate collagen and elastin production, which improves skin texture and firmness without the traditional irritating side effects.

    Water (Aqua), Butylene Glycol, Dipropylene Glycol, Cyclopentasiloxane, PEG-12 Dimethicone Crosspolymer, Dimethicone Crosspolymer, Dimethicone/Vinyl Dimethicone Crosspolymer, Dimethiconol, Dimethicone, Laureth-23, Laureth-4, Glycerin, Heparan Sulfate, Pentylene Glycol, Retinyl Safflowerate, Retinol, Lysophosphatidic Acid, Myristoyl Nonapeptide-3, Myristoyl Pentapeptide-17, Ethyl Safflowerate, Ethyl Flaxseedate, Dipalmitoyl Hydroxyproline, Allantoin, Panthenol, Hyaluronic Acid, Sodium Ascorbyl Phosphate, Alanine, Arginine HCl, Asparagine, Aspartic Acid, Cystine, Glutamic Acid, Glutamine, Histidine HCl, Isoleucine, Leucine, Lysine HCl, Acetyl Methionine, Phenylalanine, Proline, Serine, Threonine, Tryptophan, Tyrosine, Valine, Calcium Pantothenate, Folic Acid, Inositol, Niacinamide, Pyridoxal HCl, Riboflavin, Thiamine HCl, Calcium Chloride, Magnesium Sulfate, Potassium Chloride, Sodium Chloride, Sodium Phosphate, Beta-Carotene, Polysorbate 80, Polyaminopropyl Biguanide, Fragrance, Tromethamine.
Step 1

After cleansing, apply 1 - 2 pumps of Senté Bio Complete Serum on your face and rub gently.

Step 2

Allow the serum to absorb fully into the skin before moving on to the next step of your routine.

Step 3

Follow up with a moisturizer to soothe and lock in hydration.

Customer Reviews
4.9 Based on 23 Reviews
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Filter Reviews:
Patti P.
United States United States
Bio complete #1

My favorite! I can use every night without getting too dry. Paired with dermal repair, the perfect combination.

Robin A.
United States United States
Excellent product

Excellent product, takes away small bumps on my skin and smooth it out overall .

Kelly L.
United States United States
Repeat customer

I've been using this and the dermal repair cream for a pretty long time, but my doctor's office stopped carrying both. They provided me with your website. I was a little leery to purchase online, but both products are exactly as expected. I'm 51 years old and I am often complimented on the youthful appearance of my skin. I am positive skincare, such as these two great products, and "religious" use of facial sunscreen are allowing me to "age gracefully."

Anthony K.
United States United States

I use nightly and results are great.

Susan H.
United States United States
Bio Complete Serium

I have only been using this product since April, but I really love it!