SENTÉ Bio Complete Serum

With Patented Heparan Sulfate Analog Technology + Sustained Release Retinoids
30 mL/ 1.0 FL OZ

Finally, a retinol for those who do not tolerate traditional retinoids. Ideal for sensitive skin and first-time retinol users. 

What it is: A lower concentration retinol serum that improves the appearance of fine lines, wrinkles and uneven skin tone in as little as 8 weeks with minimal risk of irritation.

Why it’s special:

  • Formulated with patented Heparan Sulfate Analog (HSA) technology to rapidly and profoundly hydrate and strengthen the skin’s natural ability to repair itself Discover more about Heparan Sulfate Analog Technology
  • Great choice for anyone who would like to use retinol and has sensitive skin
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  • Lightweight, fast-absorbing formula leaves skin feeling smooth and healthy

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  • Doesn’t clog pores
  • Hypoallergenic
  • Dermatologist-tested
  • Paraben free
  • Gluten free

In a clinical Study....

100% of subjects showed improvement in skin texture in 8 weeks.


Clinical Data

In a clinical Study....

100% of subjects showed improvement in skin texture in 8 weeks.

Visible Results

  • AlphaRet-Before-1-Baseline

Main Ingredients

Heparan Sulfate Analog is a revolutionary repairing molecule that helps reduce redness, delivers deep hydration, and support the skin’s ability to repair itself

Retinol and Retinyl Safflowerate combine to help promote cell turnover to diminish the appearance of fine lines, wrinkles and uneven skin tone. The sustained release formula is designed to deliver efficacy gradually and minimize the risk of irritation commonly associated with the use of retinol creams.

All Ingredients

Water (Aqua), Butylene Glycol, Dipropylene Glycol, Cyclopentasiloxane, PEG-12 Dimethicone Crosspolymer, Dimethicone Crosspolymer, Dimethicone/Vinyl Dimethicone Crosspolymer, Dimethiconol, Dimethicone, Laureth-23, Laureth-4, Glycerin, Heparan Sulfate, Pentylene Glycol, Retinyl Safflowerate, Retinol, Lysophosphatidic Acid, Myristoyl Nonapeptide-3, Myristoyl Pentapeptide-17, Ethyl Safflowerate, Ethyl Flaxseedate, Dipalmitoyl Hydroxyproline, Allantoin, Panthenol, Hyaluronic Acid, Sodium Ascorbyl Phosphate, Alanine, Arginine HCl, Asparagine, Aspartic Acid, Cystine, Glutamic Acid, Glutamine, Histidine HCl, Isoleucine, Leucine, Lysine HCl, Acetyl Methionine, Phenylalanine, Proline, Serine, Threonine, Tryptophan, Tyrosine, Valine, Calcium Pantothenate, Folic Acid, Inositol, Niacinamide, Pyridoxal HCl, Riboflavin, Thiamine HCl, Calcium Chloride, Magnesium Sulfate, Potassium Chloride, Sodium Chloride, Sodium Phosphate, Beta-Carotene, Polysorbate 80, Polyaminopropyl Biguanide, Fragrance, Tromethamine.

Step 1
After cleansing, apply 1-2 pumps of product onto fingertips and gently rub onto skin

Step 2
Let serum absorb fully before moving on to the next step of your routine

Do not use if you are pregnant, lactating or planning to become pregnant.


I love Sente Bio-Complete Serum which contains an extremely gentle retinol and skin boosting Heparan Sulfate Analog.

Complete Your Regimen:

SENTÉ Bio Complete Serum - Sente Labs
SENTÉ Bio Complete Serum
13 reviews
13 reviews
Customer Reviews
5.0 Based on 13 Reviews
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Filter Reviews:
Murray E.
United States United States
The best line of skin care

I’ve been using Sente products for several years now and it’s by far the best line of skincare out there! Great for sensitive skin. Greatly improved the appearance of my skin.

Kirtlye S.
United States United States
Love this product

My first BIO COMPLETE SERUM I got as a present. The product is effective but doesn't have any harsh side effects. No dryness in the morning, no peeling just beautiful skin. My skincare professional is having trouble ordering it so I just got my product online. Thank you, Kirtlye Spear

Jennifer E.
United States United States
Pleasantly surprised

This was recommended to me by my dermatologist and bought it directly from Sente rather than through her office (huge mark up if I bought it through the doctor). After using for several weeks, skin feels and looks smoother and more even toned! Will definitely buy again!

United States United States
Sente Products are execellent

Was having difficulties with irritation and other unwanted side effects from other product lines, with sente all problems gone, made for for skin

United States United States
wow worth the price

I didn't expect to see results this quickly, very satisfied